Driven by the use cases of PubChemRDF and SCAIView, we have developed a first community-based clinical trial ontology (CTO) by following the OBO Foundry principles. CTO uses the Basic Formal Ontology (BFO) as the top level ontology and reuses many terms from existing ontologies. CTO has also defined many clinical trial-specific terms. The general CTO design pattern is based on the PICO framework together with two applications. First, the PubChemRDF use case demonstrates how a drug Gleevec is linked to multiple (...) clinical trials investigating Gleevec’s related chemical compounds. Second, the SCAIView text mining engine shows how the use of CTO terms in its search algorithm can identify publications referring to COVID-19-related clinical trials. Future opportunities and challenges are discussed. (shrink)

本书分别对熊十力、陈寅恪、钱钟书的阐释思想进行专门探讨和比较研究。他们的阐释思想分别代表了20世纪中国哲学、史学、文学三个学科的阐释思想所曾达到的最高成就。.

Every word signifies multiple senses. Many studies using comprehension-based measures suggest that polysemes’ senses share lexical representations, whereas homophones’ meanings correspond to distinct lexical representations. Less is known about the lexical representations of polysemes compared to homophones in language production. In this study, speakers named pictures after reading sentence fragments that primed polysemes and homophones either as direct competitors to pictures, or as indirect-competitors to pictures. Polysemes elicited equal numbers of intrusions to picture names compared to in control conditions whether (...) primed as direct competitors or as indirect-competitors. This contrasted with the finding that homophones elicited more intrusions to picture names compared to in control conditions when primed as direct competitors than when primed as indirect-competitors. These results suggest that polysemes, unlike homophones, are stored and retrieved as unified lexical representations. (shrink)

Human life is infused with different kinds of normativity (e.g. instrumental, epistemic, conventional, moral). Different theorists have proposed vastly differing views on how to conceptualize the different kinds of normativity. Whereas social domain theorists have asserted that moral, conventional, and personal kinds of normativity constitute distinct thematic domains and are viewed as such even by young children, other theorists have denied that moral and nonmoral kinds of normativity are thematically distinguishable. The current paper proposes a third approach that may show (...) a way out of the controversy. Instead of viewing normative issues as belonging to one or more distinct thematic domains, it would be more accurate, both philosophically and psychologically speaking, to recognize that any given action may be grounded in multiple, non-exclusive reasons for action. Moral, conventional, and personal reasons for action may be defined in terms of what one believes one can respectively justify to all rational interlocutors, particular social partners, and oneself. The three kinds of reasons for action may accordingly be visualized as dimensions of normativity that together comprise a three-dimensional coordinate “space of reasons.” To illustrate the dimensions approach, 16 examples are given of actions whose values vary independently on each of the three dimensions. (shrink)

Is the societal-level of analysis sufficient today to understand the values of those in the global workforce? Or are individual-level analyses more appropriate for assessing the influence of values on ethical behaviors across country workforces? Using multi-level analyses for a 48-society sample, we test the utility of both the societal-level and individual-level dimensions of collectivism and individualism values for predicting ethical behaviors of business professionals. Our values-based behavioral analysis indicates that values at the individual-level make a more significant contribution to (...) explaining variance in ethical behaviors than do values at the societal-level. Implicitly, our findings question the soundness of using societal-level values measures. Implications for international business research are discussed. (shrink)

Noise in behavior is often viewed as a nuisance: while the mind aims to take the best possible action, it is let down by unreliability in the sensory and response systems. How researchers study cognition reflects this viewpoint – averaging over trials and participants to discover the deterministic relationships between experimental manipulations and their behavioral consequences, with noise represented as additive, often Gaussian, and independent. Yet a careful look at behavioral noise reveals rich structure that defies easy explanation. First, both (...) perceptual and preferential judgments show that sensory and response noise may potentially only play minor roles, with most noise arising in the cognitive computations. Second, the functional form of the noise is both non-Gaussian and non-independent, with the distribution of noise being better characterized as heavy-tailed and as having substantial long-range autocorrelations. It is possible that this structure results from brains that are, for some reason, bedeviled by a fundamental design flaw, albeit one with intriguingly distinctive characteristics. Alternatively, noise might not be a bug but a feature: indeed, we suggest that noise is fundamental to how cognition works. Specifically, we propose that the brain approximates probabilistic inference with a local sampling algorithm, one that uses randomness to drive its exploration of alternative hypotheses. Reframing cognition in this way explains the rich structure of noise and leads to a surprising conclusion: that noise is not a symptom of cognitive malfunction but plays a central role in underpinning human intelligence. (shrink)

Taiwan was affected by an outbreak of severe acute respiratory syndrome (SARS) in early 2003. A questionnaire survey was conducted to determine (1) the perceptions of risk of SARS infection in nurses; (2) the proportion of nurses considering leaving their job; and (3) work as well as non-work factors related to nurses' consideration of leaving their job because of the SARS outbreak. Nearly three quarters (71.9%) of the participants believed they were 'at great risk of exposure to SARS', 49.9% felt'an (...) increase in workload', and 32.4% thought that people avoided them because of their job; 7.6% of the nurses not only considered that they should not care for SARS patients but were looking for another job or considering resignation. The main predictors of nurses' consideration of leaving their job were shorter tenure, increased work stress, perceived risk of fatality from SARS, and affected social relationships. The findings are important in view of potential impending threats of pandemics such as avian influenza. (shrink)

This article provides current Schwartz Values Survey (SVS) data from samples of business managers and professionals across 50 societies that are culturally and socioeconomically diverse. We report the society scores for SVS values dimensions for both individual- and societal-level analyses. At the individual-level, we report on the ten circumplex values sub-dimensions and two sets of values dimensions (collectivism and individualism; openness to change, conservation, self-enhancement, and self-transcendence). At the societal-level, we report on the values dimensions of embeddedness, hierarchy, mastery, affective (...) autonomy, intellectual autonomy, egalitarianism, and harmony. For each society, we report the Cronbach’s α statistics for each values dimension scale to assess their internal consistency (reliability) as well as report interrater agreement (IRA) analyses to assess the acceptability of using aggregated individual level values scores to represent country values. We also examined whether societal development level is related to systematic variation in the measurement and importance of values. Thus, the contributions of our evaluation of the SVS values dimensions are two-fold. First, we identify the SVS dimensions that have cross-culturally internally reliable structures and within-society agreement for business professionals. Second, we report the society cultural values scores developed from the twenty-first century data that can be used as macro-level predictors in multilevel and single-level international business research. (shrink)

Background: Poor psychosocial work environments are considered critical factors of nurses’ intention to leave their profession. Workplace injustice has been proven to increase the incidence of psychiatric morbidity among workers. However, few studies have directly investigated the effect of workplace justice on nurses’ intention to leave their profession and the population attributable risk among nurses. Objective: This study identified factors associated with workplace justice and nurses’ intention to leave the profession. Method: A cross-sectional survey was conducted using a self-administered structured (...) questionnaire. Approximately 10% of all secondary referral centers in Taiwan were stratified and randomly sampled. Multiple logistic regression and population attributable risks were preformed to assess the effect of workplace justice on nurses’ intention to leave the nursing profession. Ethical considerations: This study was approved by the Research and Ethical Committee of National Taiwan University Hospital. Only nurses who consented to the study participated in the survey. Result: A total of 2268 nurses were recruited, of whom 1417 (62.5%) satisfactorily completed the questionnaire. The participants were classified and 342 (24.1%) of them were placed into the low workplace justice group. Nurses with low workplace justice had a higher intention of leaving the profession (adjusted odds ratio = 1.34, 95% confidence interval = 1.02–1.77). “Employees’ opinions are influential in hospital’s decision making” and “employees’ performance is evaluated fairly” were the most influential factors of the participants’ intention to quit. The adjusted population attributable risk was 3.7% for low workplace justice. Conclusion: This study has identified that workplace justice is a protective factor of nurses’ leaving their current profession. A fair performance appraisal system and increased autonomy at work are warranted to dissuade nurses from leaving the nursing profession. (shrink)

En la investigación se pretende mostrar, apoyado sobre todo en Gadamer, que entre arte y religión se da un vínculo indisoluble, que dicha relación va más allá del encuentro coyuntural de ciertas épocas, y que para acceder a dicho vínculo es necesario replantear la manera como, desde una óptica fundamentalmente disyuntiva, se autocomprenden dichos conceptos. Esto supone, metodológicamente. el señalamiento de la imposibilidad de abordar dicho vínculo si se parte de la delimitación precisa de los conceptos, por lo que se (...) hace necesario más bien partir de la relación misma. Y tematicamente, implica demostrar la artificialidad de los límites en los que se debate la cultura occidental. (shrink)

Il prelievo della Biblioteca Palatina fu, nel 1623, ad un secolo circa dall'inizio della Riforma, l'atto non solo simbolico con cui si cercò di vulnerare alla radice la cultura protestante asportando la Biblioteca di Heidelberg, vanto dell'intellettualità riformata e stimata superiore perfino alla Vaticana. In una lettera del 14 luglio 1608 a Janus Gruter, bibliotecario della Palatina, Scaligero era molto esplicito nella comparazione tra le due biblioteche, simbolo delle rispettive confessioni: «Indicem bibliothecae vestrae legi. Locupletior est, et meliorum librorum quam (...) Vaticana» (Lib. VI, Ep. 434). La concreta operazione di prelievo e trasporto dei libri fino a Roma, via Monaco, affidata a Leone Allacci, andò incontro ad una serie di difficoltà, a cominciare dalla imprevista totale indisponibilità di mezzi di trasporto: i «carri» di cui ampiamente si parla nel documento che qui di seguito pubblichiamo. Che fosse così arduo reperirli, ovvero trovare qualcuno che li mettesse a disposizione, era in realtà solo un aspetto - e certo non irrilevante - della più generale ostilità che circondò l'operazione. Ostilità che Allacci stesso bene avverte («Quando passo [per le strade] - scrive - li sento sospirare e dolere intrinsecamente, se bene all'esteriore bisogna che stiano savij»), e che sarà sedata solo dal deciso intervento del conte di Tilly (su di lui ved. oltre), intervenuto direttamente a Heidelberg il 14 gennaio 1623, al fine appunto di sbloccare la situazione. Ma veniamo al documento ed alla sua esemplare vicenda. (shrink)

"A class of men who are exceedingly tiresome are those who, having traveled, talk of nothing but their adventures, the countries which they have seen or traversed, the dangers, whether real or fictitious, which they have encountered, repeating the same things an hundred times over.

Past research demonstrates that mood can influence level of perceptual processing (global vs. local). The present research shows that level of perceptual processing can influence mood as well. In four studies, we manipulated people’s level of perceptual processing using a Navon letter task (Study 1), landscape scenery (Study 2), and Google Maps Street View images (Studies 3 and 4). Results from these studies and a meta-analysis support the conclusion that global processing results in higher happiness than local processing. In conjunction (...) with previous findings that mood affects level of cognitive processing, these results suggest that the link between level of processing and mood may be reciprocal and bidirectional. (shrink)

This note is a critical response to Kentaro Fujimoto’s new conservativeness argument about truth, which centres on the notion of finite conjunction. We argue that Fujimoto’s arguments turn on a specific way of formalizing the notions of finite collection and finite conjunction in first-order logic. In particular, by instead formalizing these concepts in a natural way in set theory or in second-order logic, Fujimoto’s new conservativeness argument can be resisted.

Academic mothers perform intersected roles. They carry out their profession in workplaces, while they take the “second shift” of motherhood back to their families. The contested expectations in family and career built by the heterosexual matrix cause tension to academic mothers. We qualitatively investigate the interview data of six Chinese women academics on how they perform to negotiate their motherhood and academic work in the context of Chinese higher education, driven by the Butlerian theoretical concept of the heterosexual matrix. The (...) findings suggest that Chinese academic mothers play a zero-sum game between being mothers and being academics, deriving from their ontological responsibilities of motherhood. We conclude that in the masculine academia, these women academics help maintain the heterosexual matrix by satisfying the gender normativity when they negotiate their performances in their family and career; meanwhile, most have developed some strategies to achieve their career advancement. (shrink)

The text is based on the unpublished notes from the lectures given by Chwistek in 1931 in Lvov.